Systematic analysis of direct antiglobulin test results in post-artesunate delayed haemolysis.
Systematic analysis of direct antiglobulin test results in post-artesunate delayed haemolysis.
29 avr 2021
Post-artesunate delayed haemolysis (PADH) is common after severe malaria episodes. PADH is related to the "pitting" phenomenon and the synchronous delayed clearance of once-infected erythrocytes, initially spared during treatment. However, direct antiglobulin test (DAT) positivity has been reported in several PADH cases, suggesting a contribution of immune-mediated erythrocyte clearance. The aim of the present study was to compare clinical features of cases presenting a positive or negative DAT.