Artesunate injection dosage & administration
![](https://www.severemalaria.org/sites/mmv-smo/files/styles/nugget-mobile/public/content/paragraphs/text/images/2017-03-10/inj_as_toolkit.jpg?itok=Nt1QR1KS×tamp=1489142703)
WHO recommends parenteral artesunate in preference to quinine and artemether for the treatment of severe P. falciparum malaria in adults and children. Intravenous (IV) injection is the preferred route of administration although intramuscular (IM) injection is also possible. To ensure that healthcare providers fully understand how to prepare and administer the product, these training materials were developed to illustrate these steps and facilitate correct use of the product.
Training material toolkit
English |
Français |
Português |
User guide including dosage guidance for adults and children |
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New arginine-based formulation of injectable artesunate
![](https://www.severemalaria.org/sites/mmv-smo/files/styles/nugget-mobile/public/content/paragraphs/text/images/2025-02-05/image001.png?itok=veROv9pg×tamp=1738767453)
The new arginine-based formulation of injectable artesunate for treating severe malaria simplifies preparation and administration, reducing errors and eliminating the need for dilution. It requires just a single reconstitution step with Arginine sodium bicarbonate, maintaining a concentration of 20 mg/mL for both intravenous and intramuscular use. By streamlining the process, this advancement enables quicker treatment initiation, which is critical for reducing high mortality rates associated with severe malaria.
Please check carefully, which injectable artesunate product you are using before reading the instructions.
![User guide: Arginine-based formulation of injectable artesunate for severe malaria](https://www.severemalaria.org/sites/mmv-smo/files/styles/nugget-full-width-wide/public/content/paragraphs/full_width/images/2024-11-19/MMV%20poster%20injectable%20artesunate.png?itok=VWQM_xA4×tamp=1732027750)